補體和補體系統:
補體(complement,C)是存在于正常人和動(dòng)物血清與組織液中的一組經(jīng)活化后具有酶活性的蛋白質(zhì)。早在19世紀末Bordet即證實(shí),新鮮血液中含有一種不耐熱的成分,可輔助和補充特異性抗體,介導免疫溶菌、溶血作用,故稱(chēng)為補體。補體是由30余種可溶性蛋白、膜結合性蛋白和補體受體組成的多分子系統,故稱(chēng)為補體系統(complement system)。補體系統(complement system)是一組存在于人和脊椎動(dòng)物正常新鮮血清中的非特異性球蛋白。它與酶活性有關(guān)。補體由9種成分組成,分別命名為 C1、C2、C3、…、C9。C1又有 3個(gè)亞單位即C1q、 C1r和C1s。除C1q外,其他成分大多是以酶的前體形式存在于血清中,需經(jīng)過(guò)抗原-抗體復合物或其他因子激活后,才能發(fā)揮生物學(xué)活性作用,這叫做補體的經(jīng)典激活途徑。此外還包括替代激活途徑和凝集素激活途徑。
Pel-Freez已經(jīng)從事于生產(chǎn)和銷(xiāo)售3-4周小兔補體長(cháng)達十年。補體生產(chǎn)嚴格選用出生21-28天小兔,小兔補體配血從3-4周兔心臟刺穿獲得,之后在-70℃冷凍。補體溶化、集合、無(wú)菌過(guò)濾和瓶裝在-4℃進(jìn)行,-70℃存儲。3-4周小兔補體在大量應用如殺菌和調理檢測過(guò)程中表現出低異嗜性抗體活性。樣品可用于在實(shí)驗室評估優(yōu)化各種實(shí)驗結果。
上海華雅思創(chuàng )生物技術(shù)有限公司在中國代理銷(xiāo)售Pel-Freez公司3-4周兔補體,產(chǎn)品都按照最佳儲存條件存儲和管理,發(fā)貨及時(shí),售后跟蹤反饋。另外,公司提供相關(guān)產(chǎn)品價(jià)格、性能和使用方法等信息咨詢(xún)。我們秉承專(zhuān)心服務(wù)生命科研,為中國科研工作者提供優(yōu)質(zhì)的產(chǎn)品和服務(wù)。
產(chǎn)品英文名稱(chēng):3-4 WEEK BABY RABBIT COMPLEMENT STERILE
產(chǎn)品中文名稱(chēng):Pel-Freez 3-4周小兔補體
3-4 WEEK BABY RABBIT COMPLEMENT英文簡(jiǎn)述:
Pel-Freez has been manufacturing and marketing 3-4 week rabbit complement for decades. Now you can purchase the same high quality product directly from the manufacturing site in Rogers, Arkansas, USA. The complement is produced under controlled conditions from large pools of albino rabbits that are 21-28 days old to provide product that has low heterophile antibody activity for many applications, including use in bactericidal and opsonization assays. Samples are available to evaluate various lots in your laboratory for optimal results.
RABBIT COMPLEMENT 3-4 WEEK STE Blood is aseptically collected via cardiac puncture from 3 to 4 week old rabbits (New Zealand White, mixed sex). It is then centrifuged and frozen at -70℃. The complement is thawed, pooled, sterile filtered and bottled at 4℃ then stored at -70℃.